Motrin is a well-known and popular remedy, the active ingredient of which is ibuprofen. It belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and is used to relieve pain, reduce inflammation and lower body temperature. Let's take a closer look at the main aspects of Motrin, its dosage, side effects and difference from other ibuprofen medications.
What is Motrin?
Motrin is the brand name for a drug containing Ibuprofen, the active ingredient in Motrin, which is widely used for short-term relief of pain of various origins such as headache, toothache, menstrual pain, muscle pain and minor arthritic pain. It is also used to reduce fever.
Motrin dosage
The dosage of Motrin tablets may vary depending on the patient's age, weight, and individual needs. The standard dose for adults and children over 12 years of age is usually 200 to 400 mg every 4 to 6 hours as needed. Motrin 800 mg is a higher dose that is usually prescribed by a doctor for relief of severe pain. It is important not to exceed the maximum daily dose of 3200 mg.
Motrin vs. Ibuprofen
Although Motrin is one brand of ibuprofen, there is no significant difference in action between it and the commonly available forms of ibuprofen. The main difference may lie in price and availability.
Contraindications to the use of Motrin
- Allergic reactions: Motrin ibuprofen, like other NSAIDs, may cause allergic reactions, including anaphylaxis, especially in persons allergic to aspirin or other NSAIDs.
- Pregnancy and breast-feeding: Motrin is not recommended for use in the third trimester of pregnancy due to the risk to the fetus. During breastfeeding, the drug should also be used with caution.
- Gastrointestinal disorders: Motrin ibuprofen may cause exacerbation of peptic ulcer, gastritis and other gastrointestinal disorders.
- Cardiovascular diseases: In patients with cardiovascular diseases such as high blood pressure, heart failure or after myocardial infarction, the use of Motrin may increase the risk of cardiovascular complications.
- Kidney and liver disease: Patients with impaired kidney or liver function should avoid using Motrin tablets, as it may aggravate existing problems.
Effect of combining Motrin with other medicines
The interaction of Motrin, commonly known as ibuprofen, with other medications is an important aspect to consider when using it to relieve pain, reduce inflammation or fever. Ibuprofen belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and can interact with a number of medications, altering their effectiveness or increasing the risk of side effects. Let's take a look at some of the most significant interactions between Motrin and other drugs.
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with other NSAIDs and Aspirin: Combination of Motrin with other NSAIDs or aspirin may increase the risk of gastrointestinal bleeding and ulcers. This is because NSAIDs, including ibuprofen, can damage the gastric mucosa, and their combination exacerbates this effect.
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Anticoagulants: Ibuprofen may increase the effect of anticoagulants such as warfarin, which increases the risk of bleeding. If you are taking anticoagulants, it is important to carefully monitor prothrombin and INR levels when adding ibuprofen to your therapeutic regimen.
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Antihypertensive drugs: Ibuprofen may decrease the effectiveness of some antihypertensive drugs, including ACE inhibitors, angiotensin II receptor blockers, and diuretics. This is due to ibuprofen's effect on the kidneys, which can lead to sodium and water retention in the body.
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Lithium: Motrin may increase the plasma concentration of lithium, increasing its toxic effect. When taking these drugs concomitantly, regular monitoring of lithium levels in the blood is necessary.
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Methotrexate: Ibuprofen may increase the plasma concentration of methotrexate, increasing its toxicity. Caution and monitoring of renal and hepatic function are required when using these drugs together.
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Diuretics: Ibuprofen may reduce the effect of diuretics and antihypertensive drugs, which leads to an increase in blood pressure in some patients. This is especially true in patients with pre-existing kidney disease.
Side effects of Motrin
Side effects while taking Motrin can range from mild to serious and depend on the dosage, duration of treatment, and individual patient sensitivity.
- Gastrointestinal tract: The most common side effects are related to the gastrointestinal tract and include nausea, vomiting, dyspepsia, abdominal pain, constipation or diarrhea. In more severe cases, ulcers, bleeding, and gastrointestinal perforations may occur.
- Cardiovascular system: Ibuprofen may increase the risk of cardiovascular complications such as myocardial infarction and stroke, especially with prolonged use of high doses.
- Kidneys: Prolonged use of ibuprofen, especially in high doses, may lead to impaired renal function, which in some cases may be reversible when the drug is discontinued. Vulnerable to such effects are patients with pre-existing renal disease, as well as the elderly.
- Allergic reactions: Skin reactions, including rash, itching, urticaria and Quincke's edema, may occur in some patients. In rare cases, serious allergic reactions such as anaphylaxis may occur.
- Hepatotoxicity: Taking Motrin may result in increased levels of liver enzymes, indicating possible liver damage. In very rare cases, severe liver failure may develop.
- Neurologic Reactions: Some patients experience headaches, dizziness, drowsiness or irritability. In very rare cases, severe neurologic symptoms such as aseptic meningitis may occur, especially in patients with systemic connective tissue diseases such as systemic lupus erythematosus.
- Effect on hematopoiesis: Ibuprofen may affect hematopoiesis, increasing the risk of bleeding or hematoma formation. In very rare cases, agranulocytosis, thrombocytopenia or anemia may occur.
Motrin for migraine and other uses
Motrin is often used for migraine relief due to its analgesic effects. It is also taken for other types of pain and inflammation such as arthritis, menstrual pain, and toothache.
Where and how do I buy Motrin?
Motrin can be purchased at most pharmacies without a prescription, especially in 200–400 mg tablet form. To buy higher doses, such as Motrin 800 mg, you may need a prescription from your doctor. It is also possible to order and buy Motrin online, which can be a convenient option for those who prefer home delivery or live in remote areas. When buying online, it is important to choose reliable and licensed pharmacies to avoid counterfeits. In some countries, such as Mexico, access to Motrin may be freer, and it can be purchased online without a prescription. However, it is always advisable to consult your doctor before taking any medication, especially if you are considering purchasing the product in another country.
Duration of action of Motrin
The action of Motrin begins within 30 minutes after ingestion, reaching maximum plasma concentrations in about 1–2 hours. The duration of therapeutic action of ibuprofen varies but is usually about 4–6 hours, depending on the dose, form of drug release (e.g., tablets, capsules with modified release, etc.), as well as individual physiological characteristics of the patient.
Metabolism and excretion of Ibuprofen
Motrin is metabolized in the liver with the formation of several metabolites, most of which are pharmacologically inactive. The major pathway of ibuprofen metabolism involves hydroxylation and carboxylation of the aromatic ring, after which the metabolites bind to glucuronic acid and are excreted in the urine.
Approximately 90% of an ibuprofen dose is excreted by the kidneys as metabolites or their conjugates. The remainder may be excreted with the feces. It is important to note that renal function plays a key role in the excretion of ibuprofen from the body. Therefore, in patients with impaired renal function, dose adjustment and increased intervals between doses may be required.
Factors affecting metabolism and excretion
Several factors may affect the rate of metabolism and excretion of nutrients from the body:
- Age: In the elderly, the metabolism of the drug may slow down due to decreased kidney and liver function, requiring dosage adjustments.
- Kidney and liver function: Disruption of the function of these organs may lead to slower excretion of ibuprofen, increasing the risk of side effects.
- Interaction with other drugs: Some drugs may affect the metabolism of ibuprofen, enhancing or weakening its effect, as well as increasing the risk of toxic effects.
Motrin ibuprofen is an effective medication for short-term pain relief and fever reduction. It is available in various forms and dosages, including the popular Motrin 800 mg. Despite its widespread use, possible side effects and interactions with other medications should be considered. Always consult a medical professional before starting Motrin tablets, especially if you have existing medical conditions or are taking other medications. With a responsible approach to taking Motrin, you can effectively manage your pain symptoms while minimizing health risks.
What shipping methods do you offer?
Currently there is only one shipping method available: regular airmail delivery (15-24 business days) via Mexican postal service, USPS, CANADA POST, and PARCEL FORCE.
Regular airmail is an inexpensive and reliable option.
Tracking information:
Please note that while regular airmail can also be tracked in most cases, the tracking information is available only on delivery (or attempted delivery) of the order. This allows us to see if your order was delivered successfully, but does not provide real-time delivery details.
What are your shipping rates and policies?
At the moment we offer 1 shipping option:
Regular Airmail Delivery (15-24 business days)
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.
Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).
You can view our shipping rate and other information after selecting a particular product.
Do you ship internationally?
yes
In what currency is my purchase transaction received?
The currency used will be the US dollar.
How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.
Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico
Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.
What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years
What is your return policy?
Read the refund and cancellation policy
We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.
What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.
How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.
What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.
