BUTRANS PATCHES BUPRENORPHINE 30MG 4PATCH

In stock
$570.51 USD
Short description

TRANSTEC® is indicated for the treatment of chronic pain of moderate to severe intensity, such as cancer-type pain (breast, prostate and lung cancer, among others) and non-cancer pain such as neuropathic pain (diabetic, postherpetic and HIV neuropathy, among others). , musculoskeletal (rheumatoid arthritis, osteoarthritis, low back pain, fibromyalgia, etc.), which does not respond to non-opioid analgesics. TRANSTEC® can also be used in trauma and postoperative conditions that require long-term analgesic treatment. TRANSTEC® is not suitable for the treatment of acute pain. TRANSTEC® 52.5 μg/h: Each PATCH contains 30 mg of buprenorphine. Area containing the active substance: 37.5 cm2. Nominal release rate: 52.5 μg buprenorphine per hour (over a period of up to 96 hours).

Pharmacodynamic properties: Buprenorphine is a partial μ-opioid agonist. It also has antagonistic activity at the kappa-opioid receptor. It is classified as a psychotropic substance under international convention.
 
Opioids can influence the hypothalamic-pituitary-adrenal or –gonadal axes. Some of the changes that can be observed include an increase in serum prolactin and decreases in plasma levels of cortisol and testosterone. Clinical symptoms may manifest due to these hormonal changes.
 
In vitro and animal studies indicate different effects of natural opiates, such as morphine, on components of the immune system; The clinical significance of these findings is unknown. It is unknown whether buprenorphine, a semi-synthetic opiate, has immunological effects similar to morphine.
 
Each SOLORO® 7 buprenorphine transdermal patch provides a constant supply of buprenorphine for up to 7 days. Steady state is reached during the first application on the third day. After removing the patch, buprenorphine concentrations decrease, reducing by approximately 50% in 12 hours (range 10-24 hours).
 
Absorption does not vary significantly between specified application sites. The mean exposure (AUC) at each of the application sites is within approximately +/- 11% of the mean exposure for all four sites.
 
After application of the buprenorphine transdermal patch, the active substance diffuses from the system through the skin.
 
Buprenorphine is approximately 96% bound to plasma proteins.
 
The metabolism of buprenorphine in the skin after patch application is negligible. Buprenorphine is eliminated via hepatic metabolism with subsequent biliary and renal excretion of soluble metabolites.
 
Norbuprenorphine is the only known active metabolite of buprenorphine.

What shipping methods do you offer?
Currently there is only one shipping method available: regular airmail delivery (15-24 business days) via Mexican postal service, USPS, CANADA POST, and PARCEL FORCE.

Regular airmail is an inexpensive and reliable option.

Tracking information:
Please note that while regular airmail can also be tracked in most cases, the tracking information is available only on delivery (or attempted delivery) of the order. This allows us to see if your order was delivered successfully, but does not provide real-time delivery details.

What are your shipping rates and policies?
At the moment we offer 1 shipping option:

Regular Airmail Delivery (15-24 business days)
 
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.

Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).

You can view our shipping rate and other information after selecting a particular product.

Do you ship internationally?
yes
 
In what currency is my purchase transaction received?
The currency used will be the US dollar.

How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.

Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico

Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.

What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years

What is your return policy?
Read the refund and cancellation policy

We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
 
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.

What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.

How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.

What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.

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