In stock
$245.00 USD
Short description

Narcotic pain reliever. ENDOCODIL® contains oxycodone, a phenanthrenic derivative used as an opiate analgesic, useful in the management of pain of moderate to severe intensity, acute or chronic, it is also effective in the management of postoperative pain. ENDOCODIL® is indicated for the treatment of severe pain that requires strong doses of opioids.

Endocodil is an innovative drug designed to effectively relieve pain and improve the quality of life of patients. Its main active ingredient is Oxycodone, which is a powerful analgesic that can significantly reduce the intensity of pain.

It is also known as: Endocodil, Endocodil IR and Endocodil OXY, which are different forms of the same drug with different speeds and durations of action. The choice of a particular form depends on the individual needs and characteristics of each patient. Before using either of these medications, it is important to consult with a physician to determine the most appropriate option.

Endocodil is a medication based on the active ingredient oxycodone. It is used to relieve moderate to severe pain in adult patients. Endocodil is available in a variety of dosages and forms, allowing you to find the best option for each patient.

Endocodil IR differs from regular Endocodil in that it is an immediate-release form. "IR" here stands for "Immediate Release." This means that the drug starts working faster, providing quicker pain relief. Endocodil IR is often used for short-term relief of acute pain conditions.

Endocodil OXY also contains oxycodone, but at a higher concentration and in an extended-release form. "OXY" here indicates "Oxycodone Extended-Release". This allows the drug to act longer, providing stable pain relief for a longer period of time. Endocodil OXY is generally recommended for patients who need consistent pain control over a long period of time.

Endocodil Oxycodone, in a dosage of 40 mg, is a highly effective medication designed to relieve severe pain that significantly limits a patient's usual activities. This concentration of Oxycodone provides maximum pain relief with minimal side effects.

It is used to relieve moderate to severe pain in adult patients suffering from various conditions such as cancer, trauma, post-surgical conditions and chronic diseases.


Endocodil 40 mg tablets are a convenient and easily dosed form of the drug that provides fast and long-lasting action. Each tablet contains the optimal amount of oxycodone to achieve the desired analgesic effect.

Tablets of Endocodil 40 mg are recommended for patients with moderate to severe pain symptoms caused by various diseases or conditions, such as cancer, trauma, postoperative complications or chronic pain. The drug can significantly improve the patient's quality of life, providing comfort and the ability to lead an active lifestyle.

The dosage of Endocodil oxycodone 40 mg should be determined by the doctor according to the individual needs and characteristics of each patient. It is generally recommended to start with the lowest effective dose, gradually increasing it if necessary under the supervision of a physician. Tablets are swallowed whole, without chewing, with a small amount of water.


  • Allergy: Patients with a known allergy to oxycodone or other opioid agonists should not take Endocodil.
  • Respiratory problems: The medication should be used with caution in patients with asthma, chronic lung disease, or other breathing problems.
  • Opioid dependence: Endocodil oxycodone should be avoided in patients with alcohol or drug dependence.
  • Pregnancy and lactation: Use of Endocodil OXY during pregnancy and lactation should be done only on the advice of a physician.
  • Liver or kidney problems: Patients with hepatic or renal impairment should take Endocodil with caution and under the supervision of a physician.

Side effects

  • Drowsiness and fatigue: The drug may cause drowsiness and fatigue, so it is not recommended to drive a car or engage in other dangerous activities that require increased concentration.
  • Constipation: One of the most common side effects of Endocodil is constipation. Patients are advised to increase their intake of water and fiber-rich foods to prevent this.
  • Nausea and vomiting: In some patients, the drug may cause nausea and vomiting. In this case, it is recommended to take the drug with food or as advised by a doctor.
  • Breathing problems: In some cases, Oxycodone may cause breathing problems, especially if the recommended dose is exceeded. Patients should seek immediate medical attention if breathing difficulties occur.
  • Dependence: Prolonged and uncontrolled use of Endocodil may lead to the development of physical and psychological dependence on the drug.

Duration of action of Endocodil

The duration of action of Endocodil depends on the form of the drug. For example, an extended-release formulation such as Endocodil OXY can last up to 12 hours or even longer, providing stable pain relief for a long time. While an immediate-release form, such as Endocodil IR, starts to take effect more quickly but may only remain effective for a few hours.

Methods of elimination from the body

Metabolism in the liver: Oxycodone is metabolized in the liver to form active metabolites, which are then excreted from the body through the kidneys. Proper liver function plays a key role in this process, so patients with hepatic insufficiency may require dose adjustment of the drug.

Renal excretion: Most of the oxycodone metabolites are excreted from the body through the kidneys in the form of urine. In patients with renal insufficiency, it may be necessary to reduce the dose of the drug to prevent its accumulation in the body.

Adherence to the doctor's recommendations: Patients should strictly follow the doctor's recommendations regarding the dosage and regimen of Endocodil. Uncontrolled use of the drug may lead to undesirable side effects and toxicity.

Discontinuation of the drug: If it is necessary to stop taking the drug, the doctor should conduct a gradual reduction of the dose (if such instructions are available) to prevent withdrawal syndrome and other unpleasant consequences.

Interaction of Endocodil Oxycodone with other medicines

Endocodil (oxycodone) is a powerful analgesic that may interact with other medications, which may affect their effectiveness and safety. It is important to be aware of potential interactions to avoid unwanted effects and ensure safe treatment.

  • Sedatives: Endocodil increases the sedative effects of other centrally acting drugs such as benzodiazepines, alcohol, sleeping pills and sedatives. This can lead to severe drowsiness, respiratory depression, and other dangerous effects.
  • Antianginal drugs: The use of Oxycodone concomitantly with drugs for the treatment of angina pectoris, such as nitrates, may lead to a decrease in blood pressure and the development of hypotension.
  • Antihypertensive drugs: The medicine may weaken the effect of antihypertensive drugs such as diuretics, ACE inhibitors and calcium channel blockers, which may lead to an increase in blood pressure.
  • Drugs for the treatment of depression: The use of Endocodil with antidepressants such as selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants may increase the depressant effect and increase the risk of serotonin excess syndrome.
  • Parkinson's disease drugs: The drug may increase extrapyramidal side effects of drugs used to treat Parkinson's disease, such as levodopa.

Endocodil OXY is not just an analgesic; it is the key to a new life without pain and discomfort. Thanks to the drug's high efficacy and safety, patients can enjoy an active life again without the constant suffering of pain.


What shipping methods do you offer?
Currently there is only one shipping method available: regular airmail delivery (15-24 business days) via Mexican postal service, USPS, CANADA POST, and PARCEL FORCE.

Regular airmail is an inexpensive and reliable option.

Tracking information:
Please note that while regular airmail can also be tracked in most cases, the tracking information is available only on delivery (or attempted delivery) of the order. This allows us to see if your order was delivered successfully, but does not provide real-time delivery details.

What are your shipping rates and policies?
At the moment we offer 1 shipping option:

Regular Airmail Delivery (15-24 business days)
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.

Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).

You can view our shipping rate and other information after selecting a particular product.

Do you ship internationally?
In what currency is my purchase transaction received?
The currency used will be the US dollar.

How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.

Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico

Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.

What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years

What is your return policy?
Read the refund and cancellation policy

We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.

What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.

How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.

What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.

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