Pargeverine hydrochloride is a rapidly absorbed drug. It is metabolized in the body without its metabolites having been identified, which are excreted through bile and urine.
The elimination process is relatively fast, so that it is necessary to administer repeated doses every 8 hours.
The antispasmodic effect of pargeverine hydrochloride derives from its antimuscarinic and musculotropic action. Due to its action on the contracted or distended myofibril, Pargeverine has a spasmolytic effect and is useful in the treatment of all painful visceral syndromes whose main component is the spasm of the smooth muscles located in any portion of the digestive tract of the bile ducts of the urinary tract or female genital tract.
Lysine clonixinate is a non-narcotic pain reliever, derived from anthranilic acid. It inhibits the enzyme prostaglandin synthetase, responsible for the synthesis of prostaglandins.
The prostaglandins PGE and PGF2 are directly responsible for the stimulation of pain neuroreceptors; Lysine clonixinate, by blocking its production, prevents the uptake of painful sensitivity, regardless of the cause, intensity and location. Lysine clonixinate has also been shown to inhibit bradycin and PGF2, already produced by what is considered a direct antagonist of pain mediators.
Lysine clonixinate has an analgesic effect, without altering the vital signs or the state of consciousness of the patients, since it is a non-narcotic analgesic. 125 mg dose of lysine clonixinate is 23.6 times higher than acetylsalicylic acid and 10 times higher compared to metamizole.
It does not depress the bone marrow or interfere with clotting factors, so it does not alter bleeding time.
Lysine clonixinate is rapidly and completely absorbed in the stomach, starting its activity within the first 10 to 15 minutes after ingestion, reaching maximum serum concentrations at the time of administration. It is not deposited in the gastric mucosa, therefore it has a minimal ulcerogenic index. It is widely distributed in all tissues. It is partially metabolized in the liver and is eliminated via the urine.
In those cases in which the differential diagnosis between visceral pain and somatic pain is imprecise or when both overlap, Pargeverine, lysine clonixinate, exerts antispasmodic and analgesic effects, normalizing myotone and visceral motility.
Pargeverine, Lysine Clonixinate, exerts an analgesic effect on the affected areas and reflex zones, effectively blocking the visceral spasm-pain cycle.
What shipping methods do you offer?
Currently there is only one shipping method available: regular airmail delivery (10-12 business days) via Mexican postal service, USPS, CANADA POST, and PARCEL FORCE.
Regular airmail is an inexpensive and reliable option.
Tracking information:
Please note that while regular airmail can also be tracked in most cases, the tracking information is available only on delivery (or attempted delivery) of the order. This allows us to see if your order was delivered successfully, but does not provide real-time delivery details.
What are your shipping rates and policies?
At the moment we offer 1 shipping option:
Regular Airmail Delivery (10-12 business days)
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.
Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).
You can view our shipping rate and other information after selecting a particular product.
Do you ship internationally?
yes
In what currency is my purchase transaction received?
The currency used will be the US dollar.
How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.
Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico
Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.
What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years
What is your return policy?
Read the refund and cancellation policy
We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.
What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.
How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.
What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.
