Clonazepam exhibits pharmacological properties that are common to benzodiazepines, including anticonvulsant, sedative, muscle relaxant, and anxiolytic effects. As with other benzodiazepines, its effects are believed to be primarily due to GABA-mediated postsynaptic inhibition, although some animal studies also show an effect on serotonin.
Data from animal models and some electroencephalographic studies in man have shown that clonazepam rapidly suppresses many types of paroxysmal activity, including spike-and-wave discharge in absence seizures (petit mal), slow spike waves, slow spike waves, generalized spikes, spikes with temporal or other locations, as well as irregular waves and spikes.
Generalized EEG normalities are suppressed more regularly than focal abnormalities. In agreement with this, clonazepam has beneficial effects in generalized and focal epilepsies.
Clonazepam is well absorbed from the gastrointestinal tract. In one study, peak blood concentrations found after 1 to 2 hours were 6.5-13.5 ng/mL when a single 2 mg oral dose of micronized clonazepam was administered to healthy adults. However, in some individuals the maximum concentration was found between 4 to 8 hours. Although the concentration of clonazepam required in plasma to obtain a therapeutic effect has not been established, some studies indicate that it may be between 20-80 ng/ml. Plasma concentrations in this range can be maintained in adults by administering clonazepam 6 mg daily in three divided doses and in children 6 to 13 years of age with 1.5-4 mg of the drug daily in three divided doses. Usually, the action starts at 20 to 60 minutes. Its duration is 6 to 8 hours in infants and young people and more than 12 hours in adults.
There is very little information on the distribution of clonazepam and it is similar to other benzodiazepines. The drug appears to cross the placenta and the blood-brain barrier.
Clonazepam is metabolized in the liver to various metabolites including 7-aminoclonazepam, 7-acetaminoclonazepam and 3-hydroxy derivatives of these metabolites, and clonazepam. Clonazepam metabolites are excreted in the urine, mainly by a first order reaction and together with their glucuronic and/or sulfate conjugates. A minimal amount of the drug is excreted unchanged.
What shipping methods do you offer?
Currently there is only one shipping method available: regular airmail delivery (10-12 business days) via Mexican postal service, USPS, CANADA POST, and PARCEL FORCE.
Regular airmail is an inexpensive and reliable option.
Tracking information:
Please note that while regular airmail can also be tracked in most cases, the tracking information is available only on delivery (or attempted delivery) of the order. This allows us to see if your order was delivered successfully, but does not provide real-time delivery details.
What are your shipping rates and policies?
At the moment we offer 1 shipping option:
Regular Airmail Delivery (10-12 business days)
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.
Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).
You can view our shipping rate and other information after selecting a particular product.
Do you ship internationally?
yes
In what currency is my purchase transaction received?
The currency used will be the US dollar.
How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.
Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico
Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.
What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years
What is your return policy?
Read the refund and cancellation policy
We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.
What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.
How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.
What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.
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