The study explored the anovulatory effects of algestone and estradiol injections, investigating their duration, metabolism, and elimination patterns among women with regular ovulatory cycles. These women underwent multiple cycles of treatment involving the administration of the mentioned estrogen or progestin derivative. Across 4 to 6 treatment cycles, the hormonal formulations were administered and their effects were closely observed.
PERLUDIL
The findings of the study unveiled that both hormonal derivatives exhibited a presence in the bloodstream throughout the menstrual cycle. After the final injection, only minimal traces of estradiol enanthate were detectable 60 days later. Importantly, the elimination pathways of these hormonal derivatives and their metabolites differed significantly. Algestone acetophenide was primarily eliminated through feces, while estradiol enanthate found its route of elimination through urine.
Furthermore, the study highlighted that the excretion of estradiol enanthate and its metabolites primarily occurred in a conjugated form (approximately 80%), with a notably high glycosiduronate fraction. A marginal portion of the excreted material corresponded to the components of the formulation in their unchanged state.
The pharmacodynamics of the formulation were assessed in reproductive-age women who received monthly injections over three consecutive months. The outcomes of the study demonstrated that the treatment effectively suppressed ovulation in all cases during the treatment period. Notably, ovarian function typically returned to normal within approximately three months following the discontinuation of the drug.
In essence, this research underscores the intricate interplay between algestone and estradiol injections, shedding light on their extended presence within the body during the menstrual cycle. Additionally, the study delves into the divergent paths through which these hormonal derivatives are eliminated, emphasizing the differential routes of fecal elimination for algestone acetophenide and urinary elimination for estradiol enanthate. Furthermore, the formulation's impact on ovulation inhibition was confirmed, with ovarian function typically restoring within a few months of discontinuation.
In a world where reproductive choices are paramount, the availability of diverse contraceptive methods has revolutionized family planning. Among these options, Perludil Algestona/Estradiol 150/10mg/1ml Injection stands as a notable choice for women seeking a convenient and effective birth control solution. This injection embodies women's empowerment to make informed choices about their reproductive health.
What is Estradiol Injection? Perludil: para que sirve
Perludil Algestona Estradiol is a hormonal contraceptive that marries two active components – Algestona and Estradiol. Algestona, a synthetic progestin, and Estradiol, a synthetic estrogen, work synergistically to thwart pregnancy. Algestona inhibits ovulation, alters cervical mucus, and hinders the implantation of fertilized eggs, while Estradiol helps maintain hormonal balance and enhances the contraceptive effect.
Estradiol injection: Dosage
For Hormone Replacement Therapy (HRT) in Menopause: The typical dosage of Estradiol injection for hormone replacement therapy in menopausal women can range from 1 to 5 milligrams (mg) injected intramuscularly every one to four weeks. The dosage frequency and strength may be adjusted based on individual patient needs and responses. It's important to consult a healthcare provider before starting HRT to determine the appropriate dosage and schedule.
For Certain Medical Conditions: Estradiol injection may also be prescribed for other medical conditions, such as certain types of breast cancer or hypogonadism. In these cases, the dosage can vary widely. It's crucial to follow the specific dosage instructions provided by the healthcare provider.
Considerations Before Use
While Perludil Algestona/Estradiol Injection offers numerous benefits, certain factors should be considered before use. Women with a history of certain medical conditions, such as blood clotting disorders or certain types of cancers, may need to explore alternative contraceptive methods.
Consulting a healthcare provider is crucial to assess individual health and determine the suitability of the injection.
Benefits Beyond Contraception
Perludil advantages extend beyond pregnancy prevention. Women who experience irregular or heavy menstrual cycles find relief through hormonal regulation. Additionally, the injection may help manage conditions such as endometriosis and polycystic ovary syndrome (PCOS). However, it's important to note that individual responses may vary, and a healthcare provider's guidance is invaluable.
Estradiol injection: Side effects
It's important to be aware of potential side effects while using estradiol injection and to promptly report any unusual or severe symptoms to your healthcare provider. Here are some common side effects associated with estradiol injection:
- Injection Site Reactions: Pain, redness, swelling, or irritation at the injection site is possible. Proper injection techniques can help minimize these reactions.
- Nausea: Some individuals may experience nausea, particularly when starting estradiol treatment. Taking the injection with food may help alleviate this symptom.
- Breast Tenderness: Breast tenderness or swelling may occur, especially during the initial stages of treatment.
- Headache: Headaches are a potential side effect of estradiol treatment, but they are usually mild and temporary.
- Changes in Menstrual Cycle: Estradiol injection can affect menstrual cycles. Some individuals may experience irregular bleeding or spotting. However, others may experience a decrease in menstrual bleeding or amenorrhea (absence of menstruation).
- Mood Changes: Mood swings, irritability, or changes in emotional well-being may occur in some individuals.
- Weight Changes: Some individuals may experience weight changes, either weight gain or weight loss, while using estradiol injection.
- Fluid Retention: Fluid retention leading to bloating or swelling in the hands, feet, or ankles is a possible side effect.
- Vaginal Discomfort: Vaginal dryness or discomfort may occur, particularly in postmenopausal women.
- Skin Changes: Skin changes such as acne, rash, or darkening of the skin in certain areas may occur.
- Changes in Libido: Some individuals may experience changes in sexual desire.
- Gastrointestinal Symptoms: Upset stomach, indigestion, or abdominal discomfort can occur.
It's important to note that Estradiol injection may also carry some risks, including an increased risk of blood clots, strokes, heart attacks, and certain types of cancer. These risks may be influenced by age, personal medical history, and whether the individual smokes.
If you experience any severe or unusual side effects while using estradiol injection, such as chest pain, sudden severe headache, vision changes, or difficulty breathing, seek medical attention immediately. Your healthcare provider will be able to assess whether the benefits of estradiol treatment outweigh any potential risks or side effects, and they can guide you on proper usage and monitoring.
Estradiol Valerate Injection: How to buy online
Securing Perludil Algestona/Estradiol Injection involves visiting authorized healthcare providers or clinics. Acquiring injections from verified sources ensures authenticity, quality, and safety. The pivotal role of healthcare professionals guarantees accurate administration and the chance to address any concerns or queries. You can also buy Perludil from our online pharmacy in Mexico. We will deliver it within the specified time frame to your address
In a world that advocates for reproductive autonomy, Perludil Algestona/Estradiol 150/10mg/1ml Injection emerges as a beacon of choice. Its effectiveness, convenience, and benefits beyond contraception make it a compelling option for women seeking to responsibly manage their reproductive health. This injection bridges the gap between informed decision-making and empowered family planning, reinforcing the significance of personalized healthcare solutions. As women navigate their unique reproductive journeys, Perludil Algestona/Estradiol Injection stands as an ally in the pursuit of a balanced and fulfilling life.
What shipping methods do you offer?
Currently there is only one shipping method available: regular airmail delivery (10-12 business days) via Mexican postal service, USPS, CANADA POST, and PARCEL FORCE.
Regular airmail is an inexpensive and reliable option.
Tracking information:
Please note that while regular airmail can also be tracked in most cases, the tracking information is available only on delivery (or attempted delivery) of the order. This allows us to see if your order was delivered successfully, but does not provide real-time delivery details.
What are your shipping rates and policies?
At the moment we offer 1 shipping option:
Regular Airmail Delivery (10-12 business days)
Once your order has been shipped, we will send you an email to notify you that your product has left our facilities. From this point on, your product is only 15-24 business days.
Please note that orders are shipped on business days only (Monday through Friday, excluding holidays).
You can view our shipping rate and other information after selecting a particular product.
Do you ship internationally?
yes
In what currency is my purchase transaction received?
The currency used will be the US dollar.
How will my medication be packaged?
Your order will be properly packaged for your protection in transit to destination.
Where are the medications shipped from?
We ship from our office in Acapulco, Gro. Mexico
Where are the drugs you have to sell made?
Most of the drugs we offer are manufactured in Mexico, some are manufactured in countries such as Germany, England, France and others, all manufactured by large multinational laboratories legally established in Mexico.
What is the expiration date of the medications I receive?
We offer the guarantee that your product will have at least 10 months of use at the time of sale, however most of the drugs we sell have an expiration date greater than 1 to 2 years
What is your return policy?
Read the refund and cancellation policy
We are unable to accept credit or debit card payments as VISA and Mastercard policies (do not allow pharmacies established outside the US to sell drugs to US customers).
How do I place an order?
When you click on an ADD TO CART link, you will be directed to our secure server where you will be registered as our customer. After selecting the required product and its quantity, you will be sent an email with the information of your purchase and the information to make the payment.
What happens once I send my order?
If your payment is received and identified, you will immediately receive an order confirmation email and another email once your order has been shipped.
How do I check the status of my order?
After making your purchase, you will receive an email with your order tracking information. This email contains information about the purchase and a link to the official pages of SEPOMEX, USPS, CANADA POST and PARCEL FORCE.
What is your security and privacy policy?
We are committed to protecting your privacy with the highest level of security possible. All your personal information, including name and address, is encrypted so that it cannot be read as it is transmitted from your computer to our server. We use the Secure Socket Layer (SSL) protocol which enables end-to-end data protection.
